Crk-like protein Antibody / CrkL
Crk-like protein is a protein that in humans is encoded by the CRKL gene. This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
P46109
Host
Rabbit
Reactivity
Human
Immunogen
E. coli-derived recombinant human protein (amino acids M1-H290) was used as the immunogen for the Crk-like protein antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF, FACS, IP, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This Crk-like protein antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Crk-like protein antibody should be determined by the researcher.
Location
Cytoplasmic, nuclear
Image Legend
Frequently Asked Questions
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