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ZIP7 Antibody / HKE4 / SLC39A7

Zinc transporter SLC39A7 (ZIP7), also known as solute carrier family 39 member 7 (SLC39A7) and Histidine-rich membrane protein Ke4 (HKE4), is a protein that in humans is encoded by the SLC39A7 gene. The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunofluorescence: 5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q92504

Host

Rabbit

Reactivity

Human

Immunogen

E. coli-derived recombinant human protein (amino acids F154-Q384) was used as the immunogen for the ZIP7 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IF, Direct ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the ZIP7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This ZIP7 antibody is available for research use only.

Storage Conditions

After reconstitution, the ZIP7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the ZIP7 antibody should be determined by the researcher.

Location

Cytoplasmic (ER), nuclear

Image Legend

Immunofluorescent staining of FFPE human A549 cells with ZIP7 antibody (red) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

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