REXO2 Antibody / RNA exonuclease 2
REX2, RNA exonuclease 2 homolog (S. cerevisiae), also known as REXO2 and Oligoribonuclease, mitochondrial, is an enzyme which in humans is encoded by the REXO2 gene. This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q9Y3B8
Host
Rabbit
Reactivity
Human
Immunogen
E. coli-derived recombinant human protein (amino acids Q59-D199) was used as the immunogen for the REXO2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This REXO2 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the REXO2 antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) HeLa, 2) K562 and 3) RT4 cell lysate with REXO2 antibody. Predicted molecular weight ~27 kDa.
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