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TWEAK Antibody / Tumor necrosis factor ligand superfamily member 12

Tumor necrosis factor ligand superfamily member 12 also known as TNF-related weak inducer of apoptosis (TWEAK) is a protein that in humans is encoded by the TNFSF12 gene. Predicted to enable receptor ligand activity. Acts upstream of or within extrinsic apoptotic signaling pathway. Located in extracellular region. Is expressed in Meckel's cartilage; hip; skeleton; and superior cervical ganglion. Orthologous to several human genes including TNFSF12-TNFSF13 (TNFSF12-TNFSF13 readthrough) .

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

UniProt

O54907

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

E. coli-derived recombinant mouse protein (amino acids S46-H249) was used as the immunogen for the TWEAK antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, Direct ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the TWEAK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This TWEAK antibody is available for research use only.

Storage Conditions

After reconstitution, the TWEAK antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the TWEAK antibody should be determined by the researcher.

Image Legend

Western blot testing of 1) rat skeletal muscle, 2) rat heart and 3) mouse heart tissue lysate with TWEAK antibody. Predicted molecular weight ~27 kDa.

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