HP59 Antibody / Sialin / SLC17A5

Sialin, also known as H (+) /nitrate cotransporter and H (+) /sialic acid cotransporter, is a protein which in humans is encoded by the SLC17A5 gene. This gene encodes a membrane transporter that exports free sialic acids that have been cleaved off of cell surface lipids and proteins from lysosomes. Mutations in this gene cause sialic acid storage diseases, including infantile sialic acid storage disorder and and Salla disease, an adult form.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL; Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q9NRA2

Host

Rabbit

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

E. coli-derived recombinant human protein (amino acids M1-R365) was used as the immunogen for the HP59 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, Direct ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the HP59 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This HP59 antibody is available for research use only.

Storage Conditions

After reconstitution, the HP59 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the HP59 antibody should be determined by the researcher.

Image Legend

IHC staining of FFPE human thyroid cancer tissue with HP59 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.