Furanodiene

Furanodiene is a natural terpenoid isolated from Rhizoma Curcumae. Furanodiene plays anti-cancer effects through anti-angiogenesis and inducing ROS production, DNA strand breaks and apoptosis. Furanodiene suppresseed efflux transporter Pgp (P-glycoprotein) function and reduced Pgp protein level[1].

Product Specifications

CAS Number

[19912-61-9]

UNSPSC

12352005

Target

Apoptosis; P-glycoprotein; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/furanodiene.html

Purity

99.83

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C/C(C1)=C/CC/C(C)=C/CC2=C1OC=C2C

Molecular Formula

C15H20O

Molecular Weight

216.32

References & Citations

[1]Xiao-Yu Zhu, et al. Sensitization and synergistic anti-cancer effects of Furanodiene identified in zebrafish models. Sci Rep. 2019 Mar 14;9 (1) :4541.