Sornidipine
Sornidipine is a calcium channel blocker. Sornidipine also reduces neurogenic inflammation. Sornidipine reduces the inflow of calcium ions into cells by blocking L-type calcium channels, thereby reducing the contraction of vascular smooth muscle, leading to vasodilation and decreased blood pressure. Sornidipine can be used to study the cardiovascular system especially in hypertension and related cardiovascular diseases[1].
Product Specifications
CAS Number
[95105-77-4]
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sornidipine.html
Smiles
O[C@@H](CO1)[C@](OC2)([H])[C@@]1([H])[C@@H]2OC(C3=C(C)NC(C)=C(C(OC)=O)[C@H]3C4=C(C=CC=C4)[N+]([O-])=O)=O
Molecular Formula
C22H24N2O9
Molecular Weight
460.43
References & Citations
[1]Clifford J, et al. Permanently charged sodium and calcium channel blockers as anti-inflammatory agents.WO2011006073A1.2021-06-02
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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