Sornidipine
Product Specifications
UNSPSC Description
Sornidipine is a calcium channel blocker. Sornidipine also reduces neurogenic inflammation. Sornidipine reduces the inflow of calcium ions into cells by blocking L-type calcium channels, thereby reducing the contraction of vascular smooth muscle, leading to vasodilation and decreased blood pressure. Sornidipine can be used to study the cardiovascular system especially in hypertension and related cardiovascular diseases[1].
Target Antigen
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sornidipine.html
Smiles
O[C@@H](CO1)[C@](OC2)([H])[C@@]1([H])[C@@H]2OC(C3=C(C)NC(C)=C(C(OC)=O)[C@H]3C4=C(C=CC=C4)[N+]([O-])=O)=O
Molecular Weight
460.43
References & Citations
[1]Clifford J, et al. Permanently charged sodium and calcium channel blockers as anti-inflammatory agents.WO2011006073A1.2021-06-02
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-160980/Sornidipine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-160980/
Clinical Information
No Development Reported
CAS Number
95105-77-4
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