Klotho Antibody (Center Region)
May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity). [UniProt]
Product Specifications
UniProt
Q9UEF7
Host
Rabbit
Immunogen
A portion of amino acids 331-365 from human Klotho was used as the immunogen for the Klotho antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Klotho antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Klotho antibody is available for research use only.
CAS Number
9007-83-4
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