DLL4 Antibody (C-Terminal Region)
Delta-like protein 4 is involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-1:2000
UniProt
Q9NR61
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A portion of amino acids 608-641 from human DLL4 was used as the immunogen for the DLL4 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the DLL4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This DLL4 antibody is available for research use only.
Storage Conditions
Aliquot the DLL4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
Western blot testing of DLL4 antibody at 1:1000: Lane 1) human lung, 2) mouse kidney and 3) rat lung lysate. Predicted molecular weight ~75 kDa.
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