RGMB Antibody

Repulsive Guidance Molecule B is a member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity) . Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity) . Promotes neuronal adhesion (By similarity) . May inhibit neurite outgrowth. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:2000

UniProt

Q6NW40

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant human RGMB was used as the immunogen for the RGMB antibody.

Clonality

Polyclonal

Isotype

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the RGMB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This RGMB antibody is available for research use only.

Storage Conditions

Aliquot the RGMB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the RGMB antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of RGMB antibody at 1:2000: Lane 1) human U-251 MG, 2) (h) HEK293, 3) (h) brain and 4) mouse brain lysate. Predicted molecular weight: 48-58 kDa.