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VAV2 Antibody (N-Terminal Region)

Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity) . [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:2000

UniProt

P52735

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 123--157 from human VAV2 was used as the immunogen for the VAV2 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the VAV2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This VAV2 antibody is available for research use only.

Storage Conditions

Aliquot the VAV2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the VAV2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of VAV2 antibody at 1:2000: Lane 1) human HeLa, 2) MCF7 and 3) SH-SY5Y cell lysate. Predicted molecular weight ~100 kDa.

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