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Thrombospondin 1 Antibody

Thrombospondin is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity) . Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors (By similarity) . [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:2000

UniProt

P07996

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 820-854 from human THBS1 was used as the immunogen for the Thrombospondin 1 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Thrombospondin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Thrombospondin 1 antibody is available for research use only.

Storage Conditions

Aliquot the Thrombospondin 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Thrombospondin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Bovine

Image Legend

Western blot testing of Thrombospondin 1 antibody at 1:2000 + human MDA-MB-231 cell lysate. Expected molecular weight ~130/155~200 kDa (unmodified/glycosylated) .

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