Thrombomodulin Antibody (N-Terminal Region)

Thrombomodulin/THBD/TM/CD141 is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca) . Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:2000

UniProt

P07204

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 92-126 from human THBD was used as the immunogen for the Thrombomodulin antibody.

Clonality

Polyclonal

Isotype

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Thrombomodulin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Thrombomodulin antibody is available for research use only.

Storage Conditions

Aliquot the Thrombomodulin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Thrombomodulin antibody may be required due to differences in protocols and secondary/substrate sensitivity.