Thrombomodulin Antibody (N-Terminal Region)
Thrombomodulin/THBD/TM/CD141 is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca) . Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:2000
UniProt
P07204
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 92-126 from human THBD was used as the immunogen for the Thrombomodulin antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Thrombomodulin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Thrombomodulin antibody is available for research use only.
Storage Conditions
Aliquot the Thrombomodulin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
Western blot testing of Thrombomodulin antibody at 1:2000 + human THP1 cell lysate. Expected molecular weight ~60/100 kDa (unmodified/glycosylated) .
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