FADS2 Antibody
Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3) . Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma- linoleic acid (GLA) (18:3n-6) and stearidonic acid (18:4n-3) respectively and other desaturation steps. Highly unsaturated fatty acids (HUFA) play pivotal roles in many biological functions. It catalizes as well the introduction of a cis double bond in palmitate to produce the mono-unsaturated fatty acid sapienate, the most abundant fatty acid in sebum. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:2000
UniProt
O95864
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human FADS2 was used as the immunogen for the FADS2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Protein A affinity
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the FADS2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This FADS2 antibody is available for research use only.
Storage Conditions
Aliquot the FADS2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
Western blot testing of FADS2 antibody at 1:2000 + human liver lysate. Predicted molecular weight ~52 kDa.
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