TLR2 Antibody
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:1000
UniProt
O60603
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human TLR2 was used as the immunogen for the TLR2 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
1070CT4.2.3.2
Applications
WB
Purity
Protein G purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TLR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TLR2 antibody is available for research use only.
Storage Conditions
Aliquot the TLR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
Western blot testing of TLR2 antibody at 1:500: Lane 1) human Ramos, 2) A549 and 3) MDA-MB-231 cell lysate. Predicted molecular weight: 85-90 kDa.
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