RAB7L1 Antibody

Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans- Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS) . May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000-1:2000

UniProt

O14966

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human RAB7L1 was used as the immunogen for the RAB7L1 antibody.

Clonality

Monoclonal

Isotype

IgG1

Clone

1789CT823.71.1.1

Applications

Purity

Protein G purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the RAB7L1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This RAB7L1 antibody is available for research use only.

Storage Conditions

Aliquot the RAB7L1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the RAB7L1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.