RAB7L1 Antibody
Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans- Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS) . May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-1:2000
UniProt
O14966
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human RAB7L1 was used as the immunogen for the RAB7L1 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
1789CT823.71.1.1
Applications
WB
Purity
Protein G purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the RAB7L1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This RAB7L1 antibody is available for research use only.
Storage Conditions
Aliquot the RAB7L1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
Western blot testing of RAB7L1 antibody at 1:1000-1:2000: Lane 1) human Jurkat and 2) A431 cell lysate. Predicted molecular weight ~23 kDa.
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