H-Gly-Arg-pNA (hydrochloride)
H-Gly-Arg-pNA hydrochloride (GR-pNA hydrochloride) is a colorimetric substrate for thrombin. H-Gly-Arg-pNA is preferentially bound by thrombin and cleaves the Gly-Arg (GR) peptide sequence, releasing p-nitroaniline (pNA) that can be detected colorimetrically at 405 nm. H-Gly-Arg-pNA hydrochloride is used as a fluorescent dye to measure thrombin activity[1].
Product Specifications
CAS Number
125455-61-0
Product Name Alternative
Gly-Arg-4-NA (hydrochloride) ; GR-pNA (hydrochloride) ; GR p-itoailide (hydrochloride)
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/h-gly-arg-pna-hydrochloride.html
Smiles
O=C([C@@H](NC(CN)=O)CCCNC(N)=N)NC(C=C1)=CC=C1[N+]([O-])=O.Cl.Cl
Molecular Formula
C14H23Cl2N7O4
Molecular Weight
424.28
References & Citations
[1]Hortin G L, et al. Macromolecular chromogenic substrates for measuring proteinase activity[J]. Clinical chemistry, 2001, 47 (2) : 215-222.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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