Sedanolide

Sedanolide, a natural compound occurring in edible umbelliferous plants, possesses anti-inflammatory and antioxidant activities[1][2].

Product Specifications

CAS Number

[6415-59-4]

UNSPSC

12352005

Target

Autophagy

Type

Natural Products

Related Pathways

Autophagy

Applications

Cancer-programmed cell death

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sedanolide.html

Purity

98.81

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1OC(CCCC)C2CCCC=C21

Molecular Formula

C12H18O2

Molecular Weight

194.27

References & Citations

[1]J A Woods, et al. Sedanolide, a Natural Phthalide From Celery Seed Oil: Effect on Hydrogen Peroxide and Tert-Butyl Hydroperoxide-Induced Toxicity in HepG2 and CaCo-2 Human Cell Lines. In Vitr Mol Toxicol. Fall 2001;14 (3) :233-40.|[2]Shu-Ling Hsieh, et al. Sedanolide Induces Autophagy Through the PI3K, p53 and NF-κB Signaling Pathways in Human Liver Cancer Cells. Int J Oncol. 2015 Dec;47 (6) :2240-6.