HCoV-OC43-IN-1
HCoV-OC43-IN-1 (Compound IV-16) is a coronavirus HCoV-OC43 inhibitor. HCoV-OC43-IN-1 has antiviral efficacy (EC50: 90 nM) . HCoV-OC43-IN-1 inhibits the mRNA level and expression of viral nucleocapsid protein (NP) [1].
Product Specifications
CAS Number
2809363-81-1
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hcov-oc43-in-1.html
Purity
99.25
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
FC(F)(C1=CC(NC2=C3C=C(OCC)C=CC3=NC(NCC4OCCC4)=N2)=CC(C(F)(F)F)=C1)F
Molecular Formula
C23H22F6N4O2
Molecular Weight
500.44
References & Citations
[1]Zhou S, et al. Design, synthesis, and structure-activity relationships of a novel class of quinazoline derivatives as coronavirus inhibitors. Eur J Med Chem. 2023 Sep 25;261:115831.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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