HCoV-OC43-IN-1

HCoV-OC43-IN-1 (Compound IV-16) is a coronavirus HCoV-OC43 inhibitor. HCoV-OC43-IN-1 has antiviral efficacy (EC50: 90 nM) . HCoV-OC43-IN-1 inhibits the mRNA level and expression of viral nucleocapsid protein (NP) [1].

Product Specifications

CAS Number

[2809363-81-1]

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hcov-oc43-in-1.html

Purity

99.25

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

FC(F)(C1=CC(NC2=C3C=C(OCC)C=CC3=NC(NCC4OCCC4)=N2)=CC(C(F)(F)F)=C1)F

Molecular Formula

C23H22F6N4O2

Molecular Weight

500.44

References & Citations

[1]Zhou S, et al. Design, synthesis, and structure-activity relationships of a novel class of quinazoline derivatives as coronavirus inhibitors. Eur J Med Chem. 2023 Sep 25;261:115831.