PDK1 Monoclonal Antibody
Product Specifications
Background
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.
CAS Number
9007-83-4
Synonyms
PDK1; PDHK1; Pyruvate dehydrogenase (lipoamide) kinase isozyme 1; mitochondrial; Pyruvate dehydrogenase kinase isoform 1
Host
Mouse
Reactivity
Human,Rat,Monkey
Immunogen
Purified recombinant fragment of human PDK1 expressed in E. Coli.
Clonality
Monoclonal
Applications
WB, IHC-p, IF, ICC, FCM, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
Frequently Asked Questions
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