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JAK3 Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

CAS Number

9007-83-4

Synonyms

JAK3; Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK

Host

Mouse

Reactivity

Human,Mouse

Immunogen

Purified recombinant fragment of human JAK3 expressed in E. Coli.

Clonality

Monoclonal

Applications

WB, IF, ICC, FCM, ELISA

Stability

-20°C for one year

Concentration

1 mg/ml

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions

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