HDAC4 Monoclonal Antibody
Product Specifications
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
CAS Number
9007-83-4
Synonyms
HDAC4; KIAA0288; Histone deacetylase 4; HD4
Host
Mouse
Reactivity
Human,Mouse,Rat
Immunogen
Purified recombinant human HDAC4 (N-terminus) protein fragments expressed in E.coli.
Clonality
Monoclonal
Applications
WB
Stability
-20°C for one year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
Frequently Asked Questions
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