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TGF beta RI(Phospho Ser165) Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

CAS Number

9007-83-4

Synonyms

TGF-beta receptor type-1; TGFBR1; ALK5; SKR4; TGF-beta receptor type-1; TGFR-1; Activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ALK-5; ALK5; Serine/threonine-protein kinase receptor R4; SKR4; TGF-beta type I receptor; Transfor

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human TGF beta Receptor I around the phosphorylation site of Ser165. AA range:131-180

Clonality

Polyclonal

Applications

WB, IHC-p, IF, ICC, ELISA

Stability

-20°C for 1 year

Concentration

1 mg/ml

Molecular Weight

55960

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

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