SphK2(Phospho Thr614) Polyclonal Antibody
Product Specifications
Background
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
CAS Number
9007-83-4
Synonyms
Sphingosine kinase 2; SPHK2; Sphingosine kinase 2; SK 2; SPK 2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human SPHK2 around the phosphorylation site of Thr614. AA range:580-629
Clonality
Polyclonal
Applications
IHC-p, IF, WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
69217
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
Frequently Asked Questions
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