RBBP6 Polyclonal Antibody

The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.

E3 ubiquitin-protein ligase RBBP6 ;EC 6.3.2.-;Proliferation potential-related protein;Protein P2P-R;Retinoblastoma-binding Q protein 1;RBQ-1;Retinoblastoma-binding protein 6;p53-associated