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Rb(Phospho Thr826) Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

CAS Number

9007-83-4

Synonyms

Retinoblastoma-associated protein; RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Retinoblastoma around the phosphorylation site of Thr826. AA range:601-650

Clonality

Polyclonal

Applications

WB, IHC-p, IF, ICC, ELISA

Stability

-20°C for 1 year

Concentration

1 mg/ml

Molecular Weight

106159

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions

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