PLCD1 Polyclonal Antibody

This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 ;EC 3.1.4.11;Phosphoinositide phospholipase C-delta-1;Phospholipase C-III;PLC-III;Phospholipase C-delta-1;PLC-delta-1