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p70 S6 Kinase alpha(Phospho Thr421) Polyclonal Antibody

Product Specifications

Background

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

CAS Number

9007-83-4

Synonyms

Ribosomal protein S6 kinase beta-1; RPS6KB1; STK14A; Ribosomal protein S6 kinase beta-1; S6K-beta-1; S6K1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinas

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human p70 S6 kinase α (phospho Thr421)

Clonality

Polyclonal

Applications

WB, IHC-p, IF, ELISA

Stability

-20°C for 1 year

Concentration

1 mg/ml

Molecular Weight

59140

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions

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