NOS1(Phospho Ser852) Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms
CAS Number
9007-83-4
Synonyms
Nitric oxide synthase brain; NOS1; Nitric oxide synthase; brain; Constitutive NOS; NC-NOS; NOS type I; Neuronal NOS; N-NOS; nNOS; Peptidyl-cysteine S-nitrosylase NOS1; bNOS
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human n-NOS around the phosphorylation site of Ser852. AA range:818-867
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ICC, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
160559
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
Frequently Asked Questions
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