IRF-3(Phospho Ser385) Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
CAS Number
9007-83-4
Synonyms
Interferon regulatory factor 3; IRF3; Interferon regulatory factor 3; IRF-3
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human IRF-3 around the phosphorylation site of Ser385. AA range:351-400
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ICC, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
47219
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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