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Histone H2A(Phospho Thr121) Polyclonal Antibody

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.

CAS Number

9007-83-4

Synonyms

Histone H2A type 1-B/E; HIST1H2AG; H2AFP; HIST1H2AI; H2AFC; HIST1H2AK; H2AFD; HIST1H2AL; H2AFI; HIST1H2AM; H2AFN; Histone H2A type 1; H2A.1; Histone H2A/p; HIST1H2AB; H2AFM; HIST1H2AE; H2AFA; Histone H2A type 1-B/E; Histone H2A.2; Histone H2A/a; Histone H2A/m; HIS

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Histone H2A around the phosphorylation site of Thr121. AA range:81-130

Clonality

Polyclonal

Applications

WB, IHC-p, IF, ELISA

Stability

-20°C for 1 year

Concentration

1 mg/ml

Molecular Weight

14091

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions

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