HASP Polyclonal Antibody
Product Specifications
Background
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,Required for normal alignment of chromosomes at metaphase. Phosphorylates histone H3 'Thr-3' during mitosis.,PTM:Autophosphorylated on both serine and threonine residues (By similarity). Phosphorylated during mitosis. Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Haspin subfamily.,Contains 1 protein kinase domain.,tissue specificity:Strongly expressed in testis. Also present in thymus and bone marrow and low levels observed in prostate, intestine, lung, spleen and lymph node. Expressed in fetal skin, liver, kidney and small intestine and also in proliferating but not non-proliferating cell lines.,
CAS Number
9007-83-4
Synonyms
Serine/threonine-protein kinase haspin ;EC 2.7.11.1;Germ cell-specific gene 2 protein;H-haspin;Haploid germ cell-specific nuclear protein kinase
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 270-350
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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