GUC2B Polyclonal Antibody

This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys.

Guanylate cyclase activator 2B [Cleaved into: Guanylate cyclase C-activating peptide 2 ;Guanylate cyclase C-activating peptide II;GCAP-II; Uroguanylin ;UGN]