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GEMI2 Polyclonal Antibody

Product Specifications

Background

This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

CAS Number

9007-83-4

Synonyms

Gem-associated protein 2 ;Gemin-2;Component of gems 2;Survival of motor neuron protein-interacting protein 1;SMN-interacting protein 1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human protein . at AA range: 150-230

Clonality

Polyclonal

Applications

WB, ELISA

Stability

-20°C for 1 year

Concentration

1 mg/ml

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions

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