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FKBP5 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Synonyms

Peptidyl-prolyl cis-trans isomerase FKBP5 ;PPIase FKBP5;EC 5.2.1.8;51 kDa FK506-binding protein;51 kDa FKBP;FKBP-51;54 kDa progesterone receptor-associated immunophilin;Androgen-regulated

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Applications

WB, ELISA

Stability

-20°C for 1 year

Concentration

1 mg/ml

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions

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