FKBP5 Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
Peptidyl-prolyl cis-trans isomerase FKBP5 ;PPIase FKBP5;EC 5.2.1.8;51 kDa FK506-binding protein;51 kDa FKBP;FKBP-51;54 kDa progesterone receptor-associated immunophilin;Androgen-regulated
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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