FCRL2 Polyclonal Antibody

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Fc receptor-like protein 2 ;FcR-like protein 2;FcRL2;Fc receptor homolog 2;FcRH2;IFGP family protein 4;Immunoglobulin receptor translocation-associated protein 4;SH2 domain-containing phos