Dok-2(Phospho Tyr345) Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.
CAS Number
9007-83-4
Synonyms
Docking protein 2; DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56;dok-2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human Dok-2 (phospho Tyr345)
Clonality
Polyclonal
Applications
IHC-p, IF, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
45379
Antibody Type
Primary antibody
Isotype
IgG
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