Cdc25A(Phospho Ser124) Polyclonal Antibody
Product Specifications
Background
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
M-phase inducer phosphatase 1; CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CDC25A around the phosphorylation site of Ser124. AA range:90-139
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
59087
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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