CCL23 Polyclonal Antibody

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms.

C-C motif chemokine 23 ;CK-beta-8;CKB-8;Macrophage inflammatory protein 3;MIP-3;Myeloid progenitor inhibitory factor 1;MPIF-1;Small-inducible cytokine A23 [Cleaved into: CCL23;19-99; CCL