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CBX8 Polyclonal Antibody

Product Specifications

Background

Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.,Contains 1 chromo domain.,subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1/hPRC-H) at least composed of PCGF2/RNF110, BMI1/PCGF4, CBX2/M33, CBX4/PC2, CBX8/PC3, PHC1, PHC2, PHC3, SCMH1, RING1 and RNF2/RING2. Interacts with MLLT3.,

CAS Number

9007-83-4

Synonyms

Chromobox protein homolog 8 ;Polycomb 3 homolog;Pc3;hPc3;Rectachrome 1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 140-220

Clonality

Polyclonal

Applications

WB, ELISA

Stability

-20°C for 1 year

Concentration

1 mg/ml

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions

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