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c-Src(Phospho Tyr419) Polyclonal Antibody

Product Specifications

Background

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

CAS Number

9007-83-4

Synonyms

Proto-oncogene tyrosine-protein kinase Src; SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human c-Src (phospho Tyr419)

Clonality

Polyclonal

Applications

WB, IHC-p, IF, ELISA

Stability

-20°C for 1 year

Concentration

1 mg/ml

Molecular Weight

59704

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions

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