ADAM8 Polyclonal Antibody

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins| and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions| including fertilization| muscle development| and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration| and it is thought to be a target for allergic respiratory diseases| including asthma. Alternative splicing results in multiple transcript variants.