VATO Rabbit Polyclonal Antibody

This gene encodes a portion of the V0 domain of vacuolar ATPase (V-ATPase)| a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Activity of this enzyme is necessary for such varied processes as protein sorting| zymogen activation| receptor-mediated endocytosis| and synaptic vesicle proton gradient generation. Alternative splicing results in multiple transcript variants.