RNF4 Rabbit Polyclonal Antibody

The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with| and inhibit the activity of| TRPS1| a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein| and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.