RhoA(Phospho Ser188) Rabbit Polyclonal Antibody

This gene encodes a member of the Rho family of small GTPases| which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape| attachment| and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.