PLC gamma2(Phospho-Tyr759) Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4|5-bisphosphate to 1D-myo-inositol 1|4|5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation| antibody deficiency| and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
CAS Number
9007-83-4
Synonyms
PLCγ2 ;Tyr759; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase gamma-2; EC 3.1.4.11; Phosphoinositide phospholipase C-gamma-2; Phospholipase C-IV; PLC-IV; Phospholipase C-gamma-2; PLC-gamma-2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized phosho peptide around human PLCγ2 (Tyr759)
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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